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METASPACE: a community-populated knowledge base of spatial metabolomes in health and disease
The effects of this can be seen in several major organs (5)
JAMA 1972
KD also enhances the antitumor effects of PD-1 blockade alone or in combination with anti-CTLA-4 antibodies
Brenner's team discovered that the antioxidant GSH produced by T cells serves not only as a garbage collector to dispose of reactive oxygen species (ROS) and free radicals, but also as a key switch for energy metabolism that controls the immune response, and is thus of high relevance to various diseases
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